Job description
Title: Associate or Sr. Associate Scientist- Formulation Development
Status: 12-month contract
Location: Onsite Monday through Friday Watertown, MA
Hourly rate: $38-$40 depending on experience
A Therapeutic clinical-stage biopharmaceutical company that is making daily pills a thing of the past. Our team has developed the first ultra-long acting pill that lasts a week or longer and can provide a wide range of medicines in a familiar oral capsule form. Our near-term focus is on addressing unmet needs where compliance is a documented issue and weekly or monthly doses would improve medication adherence and health outcomes. Current pipeline includes therapies for Alzheimer’s disease, HIV, opioid use disorder, and schizophrenia.
Position Summary
Novel ultra-long acting oral drug delivery platform uniquely combines three key elements: 1) controlled drug delivery from polymeric matrices, 2) traditional and non-traditional formulation processes, and 3) dynamic structural features providing gastric residence. As such, the individual in this role will be part of an interdisciplinary team supporting pre-clinical and clinical programs through product design, research, and development. Specifically, the Formulation Development group uses theoretical principles of chemistry, materials science, and engineering coupled with chemical and physical assays to define and characterize the drug delivery components of oral dosage forms with the highest level of rigor and quality. Additionally, we aid the process development and clinical manufacturing operations for these compositions. Clear communication/documentation, strong attention to detail, and competency in the design, execution, analysis, and progression of experiments are expected. Innovation and team collaboration are essential. A strong grounding in chemistry or materials science is valuable. This Associate position will be reporting to a Scientist or Director within the Formulation Development group.
Role and Responsibilities (include, but are not limited to):
Key Qualifications
Status: 12-month contract
Location: Onsite Monday through Friday Watertown, MA
Hourly rate: $38-$40 depending on experience
A Therapeutic clinical-stage biopharmaceutical company that is making daily pills a thing of the past. Our team has developed the first ultra-long acting pill that lasts a week or longer and can provide a wide range of medicines in a familiar oral capsule form. Our near-term focus is on addressing unmet needs where compliance is a documented issue and weekly or monthly doses would improve medication adherence and health outcomes. Current pipeline includes therapies for Alzheimer’s disease, HIV, opioid use disorder, and schizophrenia.
Position Summary
Novel ultra-long acting oral drug delivery platform uniquely combines three key elements: 1) controlled drug delivery from polymeric matrices, 2) traditional and non-traditional formulation processes, and 3) dynamic structural features providing gastric residence. As such, the individual in this role will be part of an interdisciplinary team supporting pre-clinical and clinical programs through product design, research, and development. Specifically, the Formulation Development group uses theoretical principles of chemistry, materials science, and engineering coupled with chemical and physical assays to define and characterize the drug delivery components of oral dosage forms with the highest level of rigor and quality. Additionally, we aid the process development and clinical manufacturing operations for these compositions. Clear communication/documentation, strong attention to detail, and competency in the design, execution, analysis, and progression of experiments are expected. Innovation and team collaboration are essential. A strong grounding in chemistry or materials science is valuable. This Associate position will be reporting to a Scientist or Director within the Formulation Development group.
Role and Responsibilities (include, but are not limited to):
- Plan and execute experiments using pharmaceutical sciences and engineering techniques
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- Design formulations for long acting gastric release
- Produce polymeric matrices using processes such as hot melt extrusion, film deposition, spray coating, and spray drying
- Characterize formulations for chemical, physical, processing, and stability attributes
- Apply chemical and mechanical principles to investigate and optimize formulations
- Work closely with engineering, process, and analytical teams
- Communicate findings internally
- Written: clear plans and reports for R&D programs
- In small groups: productive and collaborative discussions
- Department- and company-wide: focused presentations
- Be accountable for, and complete and accurate with data, communication, and timelines
- Help discover and develop novel approaches to control drug release and gastric residence
Key Qualifications
- B.A., B.Sc., or M.S. with a minimum of 3-5 years laboratory/formulation experience
- Degree in Chemistry, Chemical Engineering, Bio/Biomedical engineering, Materials Science, or related field
- Flexible, detailed, and careful bench scientist
- Knowledge of drug development, pharmacology, CMC, or regulatory a plus
- Demonstrated ability to work independently, following protocols without supervision
- Independently troubleshoot and deliver results with minimal direction
- Prioritize, plan, and organize work to meet deadlines and evolving priorities
- Exceptional written and oral communication skills which support an eagerness to engage colleagues, learn quickly, and grow